Ozempic vs Wegovy: Which Is Better in 2026?
Comparing Ozempic and Wegovy side by side — weight loss results, side effects, cost, dosing, and who should choose each.
| Category | Ozempic | Wegovy |
|---|---|---|
| Active Ingredient | Semaglutide | Semaglutide |
| Mechanism | GLP-1 receptor agonist | GLP-1 receptor agonist |
| FDA Approved For | Type 2 diabetes | Chronic weight management ✓ |
| Administration | Once weekly injection | Once weekly injection |
| Starting Dose | 0.25mg weekly | 0.25mg weekly |
| Maximum Dose | 2mg weekly | 2.4mg weekly ✓ |
| Average Weight Loss | ~12-15% of body weight | ~15-17% of body weight ✓ |
| Titration Schedule | 4 dose steps over 16+ weeks | 5 dose steps over 16-20 weeks |
| A1C Reduction | ~1.5-1.8% | Not primary endpoint |
| Monthly Cost (US, no insurance) | ~$900-1,000 | ~$1,300-1,400 |
| BMI Requirement | None (diabetes diagnosis needed) | BMI ≥30 or ≥27 with comorbidity |
| Cardiovascular Benefit | Proven MACE reduction (SUSTAIN-6) | Proven MACE reduction (SELECT trial) ✓ |
| Clinical Trial | SUSTAIN series | STEP series |
Track Ozempic or Wegovy with Enzo
Dose tracking, side effect logging, and a cute cat cheering you on. Free to download.
Enzo's Tip
Same semaglutide, different label! If you have type 2 diabetes, Ozempic is your match. If weight management is the primary goal, Wegovy is specifically designed for that. Either way, Enzo is here to track your progress and remind you of injection day — this cat doesn't judge, just supports!
Choose Ozempic if you...
- • Have insurance that covers it
- • Want an established track record
- • Prefer a well-known medication
Choose Wegovy if you...
- • Want maximum weight loss potential
- • Have tried other GLP-1s without success
- • Your doctor recommends it
Know which medication you want? Get prescribed from home.
Licensed providers, same-day consultations, medication shipped to your door.
See Pricing & Availability →
Never miss a dose. Enzo keeps you on track.
Dose tracking, side effect logging, and a cute cat cheering you on. Free to download.
Frequently Asked Questions
The guide your doctor doesn't have time to give you
90-day GLP-1 playbook, 30 high-protein recipes for zero-appetite days, and side effect fixes that actually work. Free.
No spam. Unsubscribe anytime.
Medical Disclaimer: Enzo is a tracking companion, not a doctor. Always consult your healthcare provider before starting, stopping, or changing any medication. The information on this page is for educational purposes only and should not be considered medical advice. Individual results may vary.